To obtain the optimum temperature transmission from the DigniCap to the head of the patient, wet the patient's hair.

FEC:  5- Fluorouracil 600mg/m² Epirubicin  60mg/m² Cyclophosphamide 600mg/m²
Pre-cooling 30 minutes, during the treatment and post-cooling 60 minutes after Epirubicin/Cyclophosphamide.

FEC:  5- Fluorouracil 600mg/m² Epirubicin  100 mg/m² Cyclophosphamide 600mg/m²
Pre-cooling 30 minutes, during the treatment and post-cooling 120 minutes after Epirubicin/Cyclophosphamide.
    
Epirubicin  100 mg/m²
Pre-cooling 30 minutes, during the treatment and post-cooling 120-150 minutes.

Doxorubicin 75mg/m² single agent or in combinations with Cisplatin or Gemcitabine
Pre-cooling 30 minutes, during the treatment and post-cooling 60 minutes after doxorubicin.

Doxorubicin 90-100mg/m²
Pre-cooling 30 minutes, during the treatment and post-cooling 120-150 minutes.

Paclitaxel 175 mg/m² single agent in combinations with Carboplatin
Pre-cooling 30 minutes, during the treatment and post-cooling 90 minutes after Paclitaxel.

Paclitaxel 175mg/m² & Epirubicin 75mg/m² & Carboplatin
Pre-cooling 30 minutes, during the treatment and post-cooling 90 minutes after paclitaxel/epirubicin.

Paclitaxel 80mg/m²
Pre-Cooling 30 minutes, during the treatment and post-cooling 60 minutes.

Paclitaxel 100mg/m²
Pre-Cooling 30 minutes, during the treatment and post-cooling 60-90 minutes.

Docetaxel 100mg/m²  Pre-cooling 30 minutes, during the treatment and post-cooling 60 minutes.

Docetaxel 30mg/m²
Pre-cooling 30 minutes, during the treatment and post-cooling 60 minutes.

ABVD: Doxorubicin 25mg/m² & Bleomycin 10000E/m² i.m. & Vinblastin 6mg/m² & Dacarbazin 375mg/m²
Pre-cooling 30 minutes, during the treatment and post-cooling 90 minutes after Dacarbazin.

BEP: Bleomycin 30000 E i.v. & Etoposid 100mg/m² Cisplatin 20mg/m²
Pre-cooling 30 minutes, during the treatment and post-cooling 120 minutes after Etoposid.

Topotecan 1,0mg/m²
Pre-cooling 30 minutes, during the treatment and post-cooling 30 minutes.

Temperature setting  +5° C
! In case of very dense and thick hair, choose temperature setting +3º C to ensure efficient cooling of the hair bottom.
! The pre-cooling include the start up time of 20 minutes (time for cap to cool down from room temperature to treatment temperature)